MRI and MRS of the brain

MRI and MRS of the Brain

Brain development and aging

Comparative studies in rodents, non-human primates and humans

Leibniz Research Alliances
Healthy aging

Influence of anesthetics on the brain

Studies on the changes in brain metabolism
(Boretius et al., 2011, Fünfschilling et al., 2012) 

Influence of Anesthetics on Neuronal Activity and Hemodynamic Coupling - Implications for Preclinical Research (Publication and Data)

Burst Suppression and Anesthetics 
(PhD project Nikoloz Sirmpilatze)

Inflammatory and degenerative diseases of the brain

myo-inositol as a marker for (micro)-glial cell activation
(Poggi et al., 2016; Janova et al., 2018) 

Interaction of neuron and glial cells
(Supplie et al., 2017) 

Permeability of the blood-brain barrier
(Huhndorf et al., 2016; Pan et al., 2017)

Methods

• Spatially high-resolution in vivo MRT

• Multi-contrast MRI

• BOLD fMRT

• (Functional) localized magnetic resonance spectroscopy (MRS)

• Cerebral perfusion and blood-brain barrier