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Flügge G; Araya-Callis C; Garea-Rodriguez E; Stadelmann-Nessler C; Fuchs E (2014): NDRG2 as a marker protein for brain astrocytes. In: Cell Tissue Res. Online verfügbar unter download.springer.com/static/pdf/516/art%253A10.1007%252Fs00441-014-1837-5.pdf.

Fuchs, Eberhard; Flügge, Gabriele (2014): Adult Neuroplasticity: More Than 40 Years of Research. In: Neural Plasticity 2014 (5), S. 1–10.

Schmelting, Barthel; Corbach-Söhle, Silke; Kohlhause, Susan; Schlumbohm, Christina; Flügge, Gabriele; Fuchs, Eberhard (2014): Agomelatine in the tree shrew model of depression: Effects on stress-induced nocturnal hyperthermia and hormonal status. In: Eur Neuropsychopharm 24(3): 437-447. Doi: 10.1016/j.euroneuro.2013.07.010


Ambeskovic, Mirela; Fuchs, Eberhard; Beaumier, Pierre; Gerken, Michael; Metz, Gerlinde A. (2013): Hair trace elementary profiles in aging rodents and primates: links to altered cell homeodynamics and disease. In: Biogerontology 14 (5), S. 557–567.

Czéh, Boldizsár; Fuchs, Eberhard; Flügge, Gabriele (2013): Altered glial plasticity in animal models for mood disorders. In: Curr Drug Targets 14 (11), S. 1249–1261.

El-Kordi, A.; Kästner, A.; Grube, S.; Klugmann, M.; Begemann, M.; Sperling, S. et al. (2013): A single gene defect causing claustrophobia. In: Transl Psychiatry 3, S. e254.

Helms, G.; Garea-Rodriguez, E; Schlumbohm, C; König, J.; Dechent, P.; Fuchs, E; Wilke, M. (2013): Structural and quantitative neuroimaging of the common marmoset monkey using a clinical MRI system. In: J Neurosci Meth 215 (1), S. 121–131.

Papciak, Justyna; Popik, Piotr; Fuchs, Eberhard; Rygula, Rafal (2013): Chronic psychosocial stress makes rats more 'pessimistic' in the ambiguous-cue interpretation paradigm. In: Behav. Brain Res. 256, S. 305–310.


Coolen, A.; Hoffmann, K.; Barf, P.; Fuchs E; Meerlo, P. (2012): Telemetric study of sleep architecture and sleep homeostasis in the day-active tree shrew Tupaia belangeri. In: Sleep Vol 35 (6), S. 879–888.

Flügge G (2012): Neurotransmitterhypothesen. In: Gründer G und Benkert O (Hg.): Handbuch der Psychopharmakotherapie. 2. Aufl. Heidelberg, Berlin: Springer Verlag, S. 115–124.

Flügge G; Fuchs, E. (2012): Tiermodelle für affektive Störungen. In: Gründer G und Benkert O (Hg.): Handbuch der Psychopharmakotherapie. 2. Aufl. Heidelberg, Berlin: Springer Verlag, S. 245–252.

Fuchs E (2012): Verhaltenspharmakologie – Eine Übersicht. In: Gründer G und Benkert O (Hg.): Handbuch der Psychopharmakotherapie. 2. Aufl. Heidelberg, Berlin: Springer Verlag, S. 105–106.

Garea-Rodriguez E; Schlumbohm C; Czeh B; König J; Helms G; Heckmann C et al. (2012): Visualizing dopamine transporter integrity with iodine-123-FP-CIT SPECT in combination with high resolution MRI in the brain of the common marmoset. In: J Neurosci Meth (210), S. 195–201.

Hargus G; Cui Y; Dihné M; Bernreuther C; Schachner M (2012): In vitro generation of three-dimensional substrate-adherent embryonic stem cell-derived neural aggregates for application in animal models of neurological disorders. In: Curr Protoc Stem Cell Biol, S. Chapter 2:Unit2D.11.

Hoffmann, K.; Coolen, A.; Schlumbohm, C.; Meerlo, P.; Fuchs, E. (2012): Remote long-term registrations of sleep-wake rhythms, core body temperature and activity in marmoset monkeys. In: Behav Brain Res 235 (2), S. 113–123.

Lescher, J.; Paap, F.; Schultz, V.; Redenbach, L.; Scheidt, U.; Rosewich, H. et al. (2012): MicroRNA regulation in experimental autoimmune encephalomyelitis in mice and marmosets resembles regulation in human multiple sclerosis lesions. In: J Neuroimmunology (246 (1-2)), S. 27–33.

Michaelis T; Boretius S; Fuchs E (2012): In-vivo Bildgebung. In: Gründer G und Benkert O (Hg.): Handbuch der Psychopharmakotherapie. 2. Aufl. Heidelberg, Berlin: Springer Verlag, S. 143–147.

Mitura, A.; Liebert, F.; Schlumbohm, C.; Fuchs, E. (2012): Improving the energy and nutrient supply for common marmoset monkeys fed under long-term laboratory conditions. In: J Med Primatol (41 (2)), S. 82–88.

Schneider, E.; Jensen, L.R; Farcas, R.; Kondova, I.; Bontrop, R.E; Navarro, B. et al. (2012): A High Density of Human Communication-Associated Genes in Chromosome 7q31-q36: Differential Expression in Human and Non-Human Primate Cortices. In: Cytogenet Genome Res 136 (2), S. 97–106.

Schneider, E.; Mayer, S.; El Hajj, N.; Jensen, L.R; Kuss, A.W; Zischler, H. et al. (2012): Methylation and expression analyses of the 7q autism susceptibility locus genes MEST, COPG2, and TSGA14 in human and anthropoid primate cortices. In: Cytogenet Genome Res 136 (4), S. 278–287.

Schnell, C.; Janc, O.A; Kempkes, B.; Araya Callis, C.; Flügge, G.; Hülsmann, S.; Müller, M. (2012): Restraint stress intensifies interstitial K+ accumulation during severe hypoxia. In: Frontiers in Pharmacology (3:53).

Seehase, S.; Lauenstein, H-D; Schlumbohm, C.; Switalla, S.; Neuhaus, V.; Förster, C. et al. (2012): LPS-induced lung inflammation in marmoset monkeys - an acute model for anti-inflammatory drug testing. In: PLoS One 7, S. e43709.

t'Hart BA; Abbott DH; Nakamura K; Fuchs E (2012): The marmoset monkey: a multi-purpose preclinical and translational model of human biology and disease. In: Drug Discovery Today (in press).

Yamashita, A.; Fuchs, E.; Taira M; Hayashi M (2012): Somatostatin-immunoreactive senile plaque-like structures in the frontal cortex and nucleus accumbens of aged tree shrews (Tupaia belangeri) and macaque monkeys (Macaca fuscata). In: J Med Primatol 41 (3), S. 147–157.

Yee, N.; Schwarting, R.; Fuchs E; Wöhr MKW (2012): Juvenile stress potentiates aversive 22-kHz ultrasonic vocalizations and freezing during auditory fear conditioning in adult male rats. In: Stress 15 (5), S. 533–544.

Yee N; Schwarting RKW; Fuchs E; Wöhr M (2012): Increaesed affective ultrasonic communication during fear learning in adult male rats exposed to maternal immune activation. In: J Psychiatric Res 46 (9), S. 1199–1205.


Cui, Y. F.; Xu, J. C.; Hargus, G.; Jakovcevski, I.; Schachner, M.; Bernreuther, C. (2011): Embryonic stem cell-derived L1 overexpressing neural aggregates enhance recovery after spinal cord injury in mice. In: PLoS One 6 (3), S. e17126. Online verfügbar unter www.ncbi.nlm.nih.gov/entrez/query.fcgi.

Fuchs E; Flügge G (2011): Chronic stress and depression. Unter Mitarbeit von Fuchs E und Flügge G. In: C. D. Conrad (Hg.): The handbook of stress: neuropsychological effects on the brain. Chichester: Wiley-Blackwell, S. 463–479.

Kas, M. J.; Krishnan, V.; Gould, T. D.; Collier, D. A.; Olivier, B.; Lesch, K. P. et al. (2011): Advances in multidisciplinary and cross-species approaches to examine the neurobiology of psychiatric disorders. In: Eur Neuropsychopharmacol 21 (7), S. 532–544. Online verfügbar unter www.ncbi.nlm.nih.gov/entrez/query.fcgi.

Kohlhause, S.; Hoffmann, K.; Schlumbohm, C.; Fuchs, E.; Flugge, G. (2011): Nocturnal hyperthermia induced by social stress in male tree shrews. relation to low testosterone and effects of age. In: Physiol Behav 104 (5), S. 786–795. Online verfügbar unter www.ncbi.nlm.nih.gov/entrez/query.fcgi.

Koolhaas, J. M.; Bartolomucci, A.; Buwalda, B.; Boer, S. F. de; Flugge, G.; Korte, S. M. et al. (2011): Stress revisited. a critical evaluation of the stress concept. In: Neurosci Biobehav Rev 35 (5), S. 1291–1301. Online verfügbar unter www.ncbi.nlm.nih.gov/entrez/query.fcgi.

Marlatt, M. W.; Philippens, I.; Manders, E.; Czeh, B.; Joels, M.; Krugers, H.; Lucassen, P. J. (2011): Distinct structural plasticity in the hippocampus and amygdala of the middle-aged common marmoset (Callithrix jacchus). In: Exp Neurol 230 (2), S. 291–301. Online verfügbar unter www.ncbi.nlm.nih.gov/entrez/query.fcgi.

Pryce, C. R.; Aubert, Y.; Maier, C.; Pearce, P. C.; Fuchs, E. (2011): The developmental impact of prenatal stress, prenatal dexamethasone and postnatal social stress on physiology, behaviour and neuroanatomy of primate offspring. studies in rhesus macaque and common marmoset. In: Psychopharmacology (Berl) 214 (1), S. 33–53. Online verfügbar unter www.ncbi.nlm.nih.gov/entrez/query.fcgi.

Ribic, A.; Flugge, G.; Schlumbohm, C.; Matz-Rensing, K.; Walter, L.; Fuchs, E. (2011): Activity-dependent regulation of MHC class I expression in the developing primary visual cortex of the common marmoset monkey. In: Behav Brain Funct 7, S. 1. Online verfügbar unter www.ncbi.nlm.nih.gov/entrez/query.fcgi.

Seehase, S.; Schleputz, M.; Switalla, S.; Matz-Rensing, K.; Kaup, F. J.; Zoller, M. et al. (2011): Bronchoconstriction in nonhuman primates. a species comparison. In: J Appl Physiol 111 (3), S. 791–798. Online verfügbar unter www.ncbi.nlm.nih.gov/entrez/query.fcgi.

Yee, N.; Plassmann, K.; Fuchs, E. (2011): Juvenile stress impairs body temperature regulation and augments anticipatory stress-induced hyperthermia responses in rats. In: Physiol Behav 104 (3), S. 408–416. Online verfügbar unter www.ncbi.nlm.nih.gov/entrez/query.fcgi.

Yee, N.; Ribic, A.; de Roo C C; Fuchs, E. (2011): Differential effects of maternal immune activation and juvenile stress on anxiety-like behaviour and physiology in adult rats. no evidence for the "double-hit hypothesis". In: Behav Brain Res 224 (1), S. 180–188. Online verfügbar unter www.ncbi.nlm.nih.gov/entrez/query.fcgi.


Czeh, B.; Abumaria, N.; Rygula, R.; Fuchs, E. (2010): Quantitative changes in hippocampal microvasculature of chronically stressed rats. no effect of fluoxetine treatment. In: Hippocampus 20 (1), S. 174–185. Online verfügbar unter www.ncbi.nlm.nih.gov/entrez/query.fcgi.

Diaz Heijtz, R.; Fuchs, E.; Feldon, J.; Pryce, C. R.; Forssberg, H. (2010): Effects of antenatal dexamethasone treatment on glucocorticoid receptor and calcyon gene expression in the prefrontal cortex of neonatal and adult common marmoset monkeys. In: Behav Brain Funct 6, S. 18. Online verfügbar unter www.ncbi.nlm.nih.gov/entrez/query.fcgi.

Ferner, K.; Zeller, U.; Schmelting, B.; Fuchs, E. (2010): Ontogenetic and lung development in Tupaia belangeri during the early postnatal period. In: Mamm Biol (75), S. 95–105.

Fuchs E; Corbach-Söhle S: Tree shrews. Unter Mitarbeit von Corbach-Söhle S. Fuchs E. In: Hubrecht R, Kirkwood J (eds) 2010- The UFAW Handbook: The care and management of laboratory and other research animals., 9. Edition Wiley-Blackwell, Oxford.

Hu, W.; Zhang, M.; Czeh, B.; Flugge, G.; Zhang, W. (2010): Stress impairs GABAergic network function in the hippocampus by activating nongenomic glucocorticoid receptors and affecting the integrity of the parvalbumin-expressing neuronal network. In: Neuropsychopharmacology 35 (8), S. 1693–1707. Online verfügbar unter www.ncbi.nlm.nih.gov/entrez/query.fcgi.

Lucassen, P. J.; Meerlo, P.; Naylor, A. S.; van Dam, A. M.; Dayer, A. G.; Fuchs, E. et al. (2010): Regulation of adult neurogenesis by stress, sleep disruption, exercise and inflammation. Implications for depression and antidepressant action. In: Eur Neuropsychopharmacol 20 (1), S. 1–17. Online verfügbar unter www.ncbi.nlm.nih.gov/entrez/query.fcgi.

Lutgehetmann, M.; Volz, T.; Kopke, A.; Broja, T.; Tigges, E.; Lohse, A. W. et al. (2010): In vivo proliferation of hepadnavirus-infected hepatocytes induces loss of covalently closed circular DNA in mice. In: Hepatology 52 (1), S. 16–24. Online verfügbar unter www.ncbi.nlm.nih.gov/entrez/query.fcgi.

McEwen, B. S.; Chattarji, S.; Diamond, D. M.; Jay, T. M.; Reagan, L. P.; Svenningsson, P.; Fuchs, E. (2010): The neurobiological properties of tianeptine (Stablon). from monoamine hypothesis to glutamatergic modulation. In: Mol Psychiatry 15 (3), S. 237–249. Online verfügbar unter www.ncbi.nlm.nih.gov/entrez/query.fcgi.

Mitura, A.; Liebert, F.; Fuchs, E.; Schlumbohm, C.; Häbich, A.-C (2010): Zur bedarfsgerechten Ernährung von Weißbüschelaffen (Callithrix jacchus) für eine langfristige Nutzung als Versuchstiere. In: Übers Tierernährg (38), S. 55–90.

Ribic, A.; Zhang, M.; Schlumbohm, C.; Matz-Rensing, K.; Uchanska-Ziegler, B.; Flugge, G. et al. (2010): Neuronal MHC class I molecules are involved in excitatory synaptic transmission at the hippocampal mossy fiber synapses of marmoset monkeys. In: Cell Mol Neurobiol 30 (6), S. 827–839. Online verfügbar unter www.ncbi.nlm.nih.gov/entrez/query.fcgi.

Yamashita, A.; Fuchs, E.; Taira, M.; Hayashi, M. (2010): Amyloid beta (Abeta) protein- and amyloid precursor protein (APP)-immunoreactive structures in the brains of aged tree shrews. In: Curr Aging Sci 3 (3), S. 230–238. Online verfügbar unter www.ncbi.nlm.nih.gov/entrez/query.fcgi.

Zambello, E.; Fuchs, E.; Abumaria, N.; Rygula, R.; Domenici, E.; Caberlotto, L. (2010): Chronic psychosocial stress alters NPY system. different effects in rat and tree shrew. In: Prog Neuropsychopharmacol Biol Psychiatry 34 (1), S. 122–130. Online verfügbar unter www.ncbi.nlm.nih.gov/entrez/query.fcgi.


Atanasova, S.; Wieland, E.; Schlumbohm, C.; Korecka, M.; Shaw, L.; Ahsen, N. von et al. (2009): Prenatal dexamethasone exposure in the common marmoset monkey enhances gene expression of antioxidant enzymes in the aorta of adult offspring. In: Stress 12 (3), S. 215–224. Online verfügbar unter www.ncbi.nlm.nih.gov/entrez/query.fcgi.

Bartolomucci A.; Fuchs E; Koolhaas J.M; Ohl, F. (2009): Acute and chronic social defeat: stress protocols and behavioral testing. In: Mood and anxiety related phenotypes in mice: characterization using behavioral tests. Unter Mitarbeit von E. Fuchs. In: Gould T.D (Hg.): Mood and anxiety related phenotypes in mice. Neuromethods 42: Humana Press, S. 261–276.

Bartolomucci A; de Kloet ER; Fuchs E; Joels M; Landgraf R;  Leopardi R; Richter-Levin G (2009): Stress-induced depression. In: Frontiers in Neuroscience (3), S. 240–241.

Bramlage, C. P.; Schlumbohm, C.; Pryce, C. R.; Mirza, S.; Schnell, C.; Amann, K. et al. (2009): Prenatal dexamethasone exposure does not alter blood pressure and nephron number in the young adult marmoset monkey. In: Hypertension 54 (5), S. 1115–1122. Online verfügbar unter www.ncbi.nlm.nih.gov/entrez/query.fcgi.

Cooper, B.; Fuchs, E.; Flugge, G. (2009): Expression of the axonal membrane glycoprotein M6a is regulated by chronic stress. In: PLoS One 4 (1), S. e3659. Online verfügbar unter www.ncbi.nlm.nih.gov/entrez/query.fcgi.

Czéh B; Fuchs, E. (2009): Hippocampus. Unter Mitarbeit von Fuchs E. Czéh B. In: Ingram R.E. (Hg.): The International Encyclopedia of Depression. New York: Springer Publishing Company, S. 313–319.

Datson, N. A.; Morsink, M. C.; Steenbergen, P. J.; Aubert, Y.; Schlumbohm, C.; Fuchs, E.; Kloet, E. R. de (2009): A molecular blueprint of gene expression in hippocampal subregions CA1, CA3, and DG is conserved in the brain of the common marmoset. In: Hippocampus 19 (8), S. 739–752. Online verfügbar unter www.ncbi.nlm.nih.gov/entrez/query.fcgi.

Fuchs E. (2009): Neuroplasticity – a new approach to the pathophysiology of depression. Unter Mitarbeit von E. Fuchs. In: Costa e Silva J.A., Macher J.P und Olié J.P (Hg.): Neuroplasticity: New biochemical mechanisms. London: CMG, S. 1–12.

Herzog, C. J.; Czeh, B.; Corbach, S.; Wuttke, W.; Schulte-Herbruggen, O.; Hellweg, R. et al. (2009): Chronic social instability stress in female rats. a potential animal model for female depression. In: Neuroscience 159 (3), S. 982–992. Online verfügbar unter www.ncbi.nlm.nih.gov/entrez/query.fcgi.

Michaelis, T.; Abaei, A.; Boretius, S.; Tammer, R.; Frahm, J.; Schlumbohm, C.; Fuchs, E. (2009): Intrauterine hyperexposure to dexamethasone of the common marmoset monkey revealed normal cerebral metabolite concentrations in adulthood as assessed by quantitative proton magnetic resonance spectroscopy in vivo. In: J Med Primatol 38 (3), S. 213–218. Online verfügbar unter www.ncbi.nlm.nih.gov/entrez/query.fcgi.

Nyirenda, M. J.; Carter, R.; Tang, J. I.; de Vries A; Schlumbohm, C.; Hillier, S. G. et al. (2009): Prenatal programming of metabolic syndrome in the common marmoset is associated with increased expression of 11beta-hydroxysteroid dehydrogenase type 1. In: Diabetes 58 (12), S. 2873–2879. Online verfügbar unter www.ncbi.nlm.nih.gov/entrez/query.fcgi.

Perez-Cruz, C.; Simon, M.; Czeh, B.; Flugge, G.; Fuchs, E. (2009): Hemispheric differences in basilar dendrites and spines of pyramidal neurons in the rat prelimbic cortex activity- and stress-induced changes. In: Eur J Neurosci 29 (4), S. 738–747. Online verfügbar unter www.ncbi.nlm.nih.gov/entrez/query.fcgi.

Perez-Cruz, C.; Simon, M.; Flugge, G.; Fuchs, E.; Czeh, B. (2009): Diurnal rhythm and stress regulate dendritic architecture and spine density of pyramidal neurons in the rat infralimbic cortex. In: Behav Brain Res 205 (2), S. 406–413. Online verfügbar unter www.ncbi.nlm.nih.gov/entrez/query.fcgi.

Schulte-Herbruggen, O.; Fuchs, E.; Abumaria, N.; Ziegler, A.; Danker-Hopfe, H.; Hiemke, C.; Hellweg, R. (2009): Effects of escitalopram on the regulation of brain-derived neurotrophic factor and nerve growth factor protein levels in a rat model of chronic stress. In: J Neurosci Res 87 (11), S. 2551–2560. Online verfügbar unter www.ncbi.nlm.nih.gov/entrez/query.fcgi.

Hu, W.; Zhang, M.; Czeh, B.; Zhang, W.; Flugge, G. (2009): Chronic restraint stress impairs endocannabinoid mediated suppression of GABAergic signaling in the hippocampus of adult male rats. In: Brain Res Bull 85 (6), S. 374–379. Online verfügbar unter http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=21527320.


Cooper B., Werner H.B., Flügge G (2008):  Glycoprotein M6a is present in glutamatergic axons in adult rat forebrain and cerebellum. Brain Res. 1197: 1-12.


Czéh B., Perez-Cruz C., Fuchs E., Flügge G (2008): Chronic stress-induced cellular changes in the medial prefrontal cortex and their potential clinical implications: Does hemisphere location matter? Behav Brain Res. 190(1): 1-13.


Rygula R., Abumaria N., Havemann-Reinecke U., Rüther E., Hiemke C., Zernig G., Fuchs E., Flügge G (2008): Pharmacological validation of a chronic social stress model of depression in rats: effects of reboxetine, haloperidol and diazepam. Behav Pharmacol. 19(3): 183-196.


Abumaria N., Ribic A., Anacker C., Fuchs E., Flügge G (2008): Stress Upregulates TPH1 but not TPH2 mRNA in the Rat Dorsal Raphe Nucleus: Identification of Two TPH2 mRNA Splice Variants. Cell Mol Neurobiol. 28(3): 331-42.


Fuchs E., Flügge G (2008): Remodelling of neuronal networks by stress. Encyclopedia of Stress. Elsevier 2. Ed. Vol. 3: 364-370.


Fuchs E (2008): Perinatal dexamethasone. Encyclopedia of Stress. Elsevier 2. Ed. Vol. 3: 97-102.

Seress L., Abrahám H., Czéh B., Fuchs E., Léránth C (2008): Calretinin expression in hilar mossy cells of the hippocampal dentate gyrus of nonhuman primates and humans. Hippocampus. 18(4): 425-434.



Fuchs E (2007): Old and new pathophysiological mechanisms in the treatment of depression. Basic and Clinical Pharmacology and Toxicology 101 (Suppl 1): 8.


Czéh B., Müller-Keuker J.I.H., Rygula R., Abumaria N., Hiemke C., Domenici E., Fuchs E (2007): Chronic social stress inhibits cell proliferation in the adult medial prefrontal cortex: hemispheric asymmetry and reversal by fluoxetine treatment. Neuropsychopharmacol 32 (7): 1490-1503.


Czéh B, Lucassen PJ (2007): What causes the hippocampal volume decrease in depression? Are neurogenesis, glial changes and apoptosis implicated? Eur Arch Psychiatry Clin Neurosci. 257(5): 250-60.


Legros C, Chalivoix S, Gabriel C, Mocaer E, Delagrange P, Fuchs E, Malpaux B (2007):  First evidence of melatonin receptors distribution in the suprachiasmatic nucleus of tree shrew brain. Neuroendocrinol Lett 28: 267-273.


Datson N, Morsink MC, Atanasova S, Armstrong VW, Zischler H, Schlumbohm C, Dutilh BE, Huynen MA, Waegele B, Ruepp A, de Kloet ER, Fuchs E (2007):  Development of the first marmoset-specific DNA microarray (EUMAMA): a new genetic tool for large –scale expression profiling in a non-human primate. BMC Genomics. 8: 190.


Abumaria N, Flügge G, Fuchs E (2007): Animal models of depression: Their application for identifying new therapeutically active molecules. Academic Dissertation Selection, Academic Meeting of the Basic Theories of Traditional Chinese Medicine (1): 9-27.


Fuchs E (2007): Neurogenesis in the adult brain: is there an association with mental disorders?

Eur Arch Psychiatry Clin Neurosci. (257): 247-249.


Abumaria N, Rygula R, Hiemke C, Fuchs E, Havemann-Reinecke U, Ruther E, Flügge G (2007): Effect of chronic citalopram on serotonin-related and stress-regulated genes in the dorsal raphe nucleus of the rat. Eur Neuropsychopharmacol. (6-7): 417-29.


Perez-Cruz C, Müller-Keuker JIH, Heilbronner U, Fuchs E, Flügge G (2007): Morphology of pyramidal neurons in the rat prefrontal cortex: lateralized dendritic remodeling by chronic stress. Neural Plasticity 46276 .


Heilbronner U, Flügge G (2007): Modulation of neurons in the paraventricular thalamic nucleus by alpha-2 adrenoceptor agonists: evidence for physiological and morphological heterogenity. Thalamus & Related Systems 3: 293-303.



Fuchs E, Flügge G (2006): Zelluläre und molekulare Restrukturierung des Gehirns durch Stress. Biospektrum (3): 275.


Fuchs E, Flügge G (2006):  Experimental animal models for the simulation of depression and anxiety. Dialogues Clin Neurosci. 8(3): 323-33.


Rygula R, Abumaria N, Domenici E, Hiemke C, Fuchs E (2006): Effects of fluoxetine on behavioral deficits evoked by chronic social stress in rats. Behav. Brain Res. 174(1): 188-92.


Czéh B, Fuchs E, Simon M (2006): NK1 receptor antagonists under investigation for the treatment of affective disorders. Expert Opin Investig Drugs 15(5): 479-86.


Rölleke U, Flügge G, Plehm S, Schlumbohm C, Armstrong V W, Dressel R, Uchanska-Ziegler B, Ziegler A, Fuchs E, Czéh B, Walter L (2006): Differential expression of major histocompatibility complex class I molecules in the brain of a New World monkey, the common marmoset (Callithrix jacchus). Neuroimmunol. 176(1-2): 39-50.


Merkler D, Böschke R, Schmelting B, Czéh B, Fuchs E, Brück W, Stadelmann C (2006): Differential macrophage/microglia activation in neocortical EAE lesions in the marmoset. Brain Pathol. 16(2): 117-23.


Abumaria N, Rygula R, Havemann-Reinecke U, Ruther E, Bodemer W, Roos C, Flügge G (2006): Identification of Genes Regulated by Chronic Social Stress in the Rat Dorsal Raphe Nucleus. Cell Mol Neurobiol. 26(2): 145-62.


Czeh B, Simon M, Schmelting B, Hiemke C, Fuchs E (2006): Astroglial plasticity in the hippocampus is affected by chronic psychosocial stress and concomitant fluoxetine treatment. Neuropsychopharmacology 31(8): 1616-1626.


Fuchs E, Flügge G, Czéh B (2006): Remodeling of neuronal networks by stress. Front Biosci. 11: 2746-2758.


Merkler D, Schmelting B, Czéh B, Fuchs E, Brück W (2006): Myelin oligodendrocyte glycoprotein-induced EAE in the common marmoset reflects the immunopathology of pattern II multiple sclerosis lesions. Multiple Sclerosis 12: 1-6.


Seckl JR, Fuchs E (2006): Glucocorticoid hormone programming in early life and its impact on adult health. Expert Review of Endocrinology & Metabolism, Editorial 1: 3-7.


Fuchs E, Simon M, Schmelting B (2006): Pharmacology of a new antidepressant: benefit of the implication of the melatonergic system. Int Clin Psychopharmacol. 21(1): 17-20.


Boretius S, Schmelting B, Watanabe T, Merkler D, Tammer R, Czéh B, Michaelis T, Frahm J, Fuchs E (2006): Monitoring of EAE onset and progression in the common marmoset monkey by sequential high-resolution 3D MRI. NMR Biomed. 19(1): 41-42.


Rygula R, Abumaria N, Flügge G, Hiemke C, Fuchs E, Ruther E., Havemann-Reinecke U (2006): Citalopram counteracts depressive-like symptoms evoked by chronic social stress in rats. Behav. Pharmacol. 17(1): 19-29.



Alfonso J, Fernandez M, Cooper B, Flügge G, Frasch AC (2005):  The stress-regulated protein M6a is a key modulator for neurite outgrowth and filopodium/spine formation. Proc Natl Acad Sci. 102(47): 17196-201.


Abrahám H, Czéh B, Fuchs E, Seress L (2005): Mossy cells and different subpopulations of pyramidal neurons express cocaine- and amphetamine-regulated transcript (CART) peptide in the hippocampal formation of non-human primates and tree shrew. Neuroscience. 136(1): 231-240.


Palchaudhuri M, Flügge G (2005): 5-HT1A receptor expression in pyramidal neurons of cortical and limbic brain regions. Cell Tissue Res. 321(2): 159-72.


Simon M, Czéh B, Fuchs E (2005): Age-dependent susceptibility of adult hippocampal cell proliferation to chronic psychosocial stress. Brain Res. 1049(2): 244-8.


Keuker JIH, Keijser JN, Nyakas C, Luiten PGM, Fuchs E (2005): Aging is accompanied by a subfield-specific reduction of serotonergic fibers in the tree shrew hippocampal formation. J. Chem. Neuroanat. 30(4): 221-9.


Fuchs E (2005): Social stress in tree shrews as an animal model of depression: an example of a behavioral model of a CNS disorder. CNS Spectr. 10(3): 182-90.


Fuchs E, Flügge G (2005): Depressionen: Eine Störung der Neuroplastizität? Psychoneuro 31: 197-203. 


Pryce CR, Feldon J, Fuchs E, Knuesel I, Oertle T., Sengstag C, Spengler M, Weber E, Weston A, Jongen-Relo A (2005): Postnatal ontogeny of hippocampal expression of the mineralocorticoid and glucocorticoid receptors in the common marmoset monkey. Eur. J. Neurosci. 21(6): 1521-35.


Rygula R, Abumaria N, Flügge G, Fuchs E, Rüther E, Havemann-Reinecke U (2005): Anhedonia and motivational deficits in rats: Impact of chronic social stress. Behav. Brain Res. 162(1): 127-34.


van der Hart MG, de Biurrun G, Czéh B, Rupniak NM, den Boer JA, Fuchs E (2005): Chronic psychosocial stress in tree shrews: effect of the substance P (NK1 receptor) antagonist L-760735 and clomipramine on endocrine and behavioral parameters. Psychopharmacology (Berl). 181(2): 207-16.


Czéh B, Pudovkina O, van der Hart MG, Simon M, Heilbronner U, Michaelis T, Watanabe T, Frahm J, Fuchs E (2005):  Examining SLV-323, a novel NK(1) receptor antagonist, in a chronic psychosocial stress model for depression. Psychopharmacology (Berl). 180(3): 548-57.


Thinyane K, Baier PC, Schindehutte J, Mansouri A, Paulus W, Trenkwalder C, Flügge G, Fuchs E (2005): Fate of pre-differentiated mouse embryonic stem cells transplanted in unilaterally 6-hydroxydopamine lesioned rats: Histological characterization of the grafted cells. Brain Res. 1045(1-2): 80-7.


Alfonso J, Frasch AC, Flügge G (2005): Chronic stress, depression and antidepressants: effects on gene transcription in the hippocampus. Rev. Neurosci. 16(1): 43-56.


Costoli T, Sgoifo A, Stilli D, Flügge G, Adriani W, Laviola G, Fuchs E, Pedrazzini T, Musso E (2005): Behavioural, neural and cardiovascular adaptations in mice lacking the NPY Y1 receptor. Neurosci. Biobehav. Rev. 29(1): 113-23.


Czéh B, Simon M, van der Hart MG, Schmelting B, Hesselink MB, Fuchs E (2005): Chronic stress decreases the number of parvalbumin-immunoreactive interneurons in the hippocampus: prevention by treatment with a substance P receptor (NK1) antagonist. Neuropsychopharmacology. 30(1): 67-79.



Fuchs E, Czéh B, Flügge G (2004): Examining novel concepts of the pathophysiology of depression in the chronic psychosocial stress paradigm in tree shrews. Behav. Pharmacol. 15(5-6): 315-25.


Heilbronner U, van Kampen M, Flügge G (2004): The alpha-2B adrenoceptor in the paraventricular thalamic nucleus is persistently upregulated by chronic psychosocial stress. Cell Mol Neurobiol. 24(6): 815-31.


Baier PC, Schindehutte J, Thinyane K, Flügge G, Fuchs E, Mansouri A, Paulus W, Gruss P, Trenkwalder C (2004): Behavioral changes in unilaterally 6-hydroxy-dopamine lesioned rats after transplantation of differentiated mouse embryonic stem cells without morphological integration. Stem Cells. 22(3): 396-404.


Alfonso J, Aguero F, Sanchez DO, Flügge G, Fuchs E, Frasch AC, Pollevick GD: Gene expression analysis in the hippocampal formation of tree shrews chronically treated with cortisol. J. Neurosci Res. 78(5): 702-10.


Fuchs E, Czéh B, Kole MH, Michaelis T, Lucassen PJ  (2004): Alterations of neuroplasticity in depression: the hippocampus and beyond. Eur. Neuropsychopharmacol. 14( 5): 481-90.


Kole MH, Czéh B, Fuchs E (2004): Homeostatic maintenance in excitability of tree shrew hippocampal CA3 pyramidal neurons after chronic stress. Hippocampus. 14(6): 742-51.


Alfonso J, Pollevick GD, van der Hart MG, Flügge G, Fuchs E, Frasch AC (2004): Identification of genes regulated by chronic psychosocial stress and antidepressant treatment in the hippocampus. Eur J Neurosci 19(3): 659-66.


Flügge G, van Kampen M, Mijnster MJ (2004): Perturbations in brain monoamine systems during stress. Springer-Verlag : Cell and Tissue Research. 315(1): 1-14.


Kole MH, Costoli T, Koolhaas JM, Fuchs E (2004): Bidirectional shift in the cornu ammonis 3 pyramidal dendritic organization following brief stress. Neuroscience. 125(2): 337-47.


Lucassen PJ, Fuchs E, Czéh B (2004): Antidepressant treatment with tianeptine reduces apoptosis in the hippocampal dentate gyrus and temporal cortex. Biol Psychiatry. 55(8): 789-96.


Keuker JIH, de Biurrun G, Luiten PG, Fuchs E (2004): Preservation of hippocampal neuron numbers and hippocampal subfield volumes in behaviorally characterized aged tree shrews. J Comp Neurol 468(4): 509-517.



Coe CL, Kramer M, Czéh B, Gould E, Reeves AJ, Kirschbaum C, Fuchs E (2003): Prenatal stress diminishes neurogenesis in the dentate gyrus of juvenile rhesus monkeys. Biol Psychiatry. 54(10): 1025-34.


Fuchs E, Flügge G (2003): Chronic social stress: effects on limbic brain structures. Physiol. Behav. 79: 417-427.


Keuker JIH, Rochford CDP, Witter MP, Fuchs, E (2003):  A cytoarchitectonic study of the hippocampal formation of the tree shrew (Tupaia belangeri). J Chem Neuroanat 26: 1-15.


Liebetanz D, Fauser S, Michaelis T, Czéh B, Watanabe T, Paulus W, Frahm J, Fuchs E (2003): Safety aspects of chronic low-frequency transcranial magnetic stimulation based on localized proton magnetic resonance spectroscopy and histology of the rat brain. J. Psychiatr Res. 37(4): 277-286.


Flügge G, van Kampen M, Meyer H, Fuchs E (2003): Alpha-2A and 2C adrenoceptor regulation in the brain: Alpha-2A changes persist after chronic stress. Eur. J. Neurosci. 17: 917-928.


Keuker JIH, Luiten PGM, Fuchs E (2003): Preservation of hippocampal neuron numbers in aged rhesus monkeys. Neurobiology of Aging. 24: 157-165.



Van Kampen M, De Kloet ER, Flügge G, Fuchs E (2002): Blockade of glucocorticoid receptors with ORG 34116 does not normalize stress-induced symptoms in male tree shrews. Eur. J. Pharmacol. 457: 207-216.


Czéh B, Welt T, Fischer AK, Erhardt A, Schmitt W, Mueller MB, Toschi N, Fuchs E, Keck ME (2002): Chronic psychosocial stress and concomitant repetitive transcranial magnetic stimulation: effects on stress hormone levels and adult hippocampal neurogenesis. Biol. Psychiat. 52: 1057-1065.


Fuchs E, Flügge G (2002): Social stress in tree shrews. Effects on physiology, brain function, and behavior of subordinate individuals. Pharmacol Biochem Behav 73: 247-258.


Fischer AK, Czéh B, Fuchs E, Goula D, von Rosenstiel P, Almeida OFX (2002): The prototypic mineralocorticoid receptor agonist aldosterone influences neurogenesis in the dentate gyrus of the adrenalectomized rat. Brain Res. 947: 290-293.


Bartolomucci A, de Biurrun G, Czéh B, van Kampen M, Fuchs E (2002): Selective enhancement of spatial learning under chronic psychosocial stress. Eur J Neurosci 15: 1863-1866.


Kole MHP, Swan L, Fuchs E (2002): The antidepressant tianeptine persistently modulates glutamate receptor currents of the hippocampal CA3 commissural associational synapse in chronically stressed rats. Eur J Neurosci 16: 807-816.


van der Hart MGC, Czéh B, de Biurrun G, Michaelis T, Watanabe T, Natt O, Frahm J, Fuchs E (2002): Substance P receptor antagonist and clomipramine prevent stress-induced alterations in cerebral metabolites, cytogenesis in the dentate gyrus and hippocampal volume. Mol Psychiatry 7: 933-941.


Coe C L, Kramer M, Kirschbaum C, Netter P, Fuchs E (2002): Prenatal stress diminishes the cytokine response of leukocytes to endotoxin stimulation in juvenile rhesus monkeys. J Clin Endokrin Metabolism 87: 675-681.


Keuker JIH, Michaelis T, de Biurrun G, Luiten PGM, Witter MP, Fuchs E (2002): Methodological considerations when studying the aging process in the nonhuman primate brain. Erwin J M, Hof  PR (eds) Interdisciplinary Topics in Gerontology, Vol.31. Aging in Nonhuman Primates. Karger, Basel, 76-101.


Flügge P, Fuchs E, Günther E, Walter, L (2002): MHC class I genes of the tree shrew Tupaia belangeri.

Immunogenetics 53: 984-988.


Fuchs E, Czéh B, Michaelis T, de Biurrun G, Watanabe T, Frahm J (2002): Synaptic plasticity and Stablon: Structural regulation. Eur. Psychiatry. 17(3): 311-317.          


van Kampen M, Kramer M, Hiemke C, Flügge G, Fuchs E (2002): The chronic psychosocial stress paradigm in male tree shrews: Evaluation of a novel animal model for depressive disorders.

Stress 5: 37-46.



Keuker JIH, Vollmann-Honsdorf GK, Fuchs E (2001): How to use the optical fractionator: an example based on the estimation of neurons in the hippocampal CA1 and CA3 regions of tree shrews. Brain Res Protocols 7: 211-221.


Bartolomucci A, de Biurrun G, Fuchs E (2001): How tree shrews perform in a searching task: evidences for strategy use? J Comp Psychol 115: 344-350.


Czéh B, Michaelis T, Watanabe T, Frahm J, de Biurrun G, van Kampen M, Bartolomucci A, Fuchs E (2001): Stress-induced changes in cerebral metabolites, hippocampal volume and cell proliferation are prevented by antidepressant treatment with tianeptine. Proc Natl Acad Sci USA 98: 12796-801.


Michaelis T, de Biurrun G, Watanabe T, Frahm J, Ohl F, Fuchs E (2001): Gender-specific alterations of cerebral metabolites with aging and cortisol treatment. J. Psychiat. Res. 35: 231-237.


Meyer U, van Kampen M, Isovich E, Flügge G, Fuchs E (2001): Chronic psychosocial stress regulates the expression of both GR and MR mRNA in the hippocampal formation. Hippocampus 11: 329-336.


Flügge G, Kramer M, Fuchs E (2001): Chronic subordination stress in male tree shrews: replacement of testosterone affects behavior and central alpha2-adrenoceptors. Physiol. Behav. 73: 293-300.


Kole MHP, Koolhaas JM, Luiten PGM, Fuchs E (2001): High-voltage-activated Ca2+ currents and the excitability of pyramidal neurons in the hippocampal CA3 subfields in rats depend on corticosterone and time of day. Neurosci Lett 307: 53-56.


Fuchs E, Flügge G (2001): Psychosoziale Belastung hinterlässt Spuren im Gehirn. Z. Med. Psychol. 10: 99-105.


Fuchs E, Kramer M, Flügge G (2001): What are the neurobiological consequences of stress? Broom DM (ed): Coping with Challenge: Welfare in Animals including Humans. Dahlem University Press, 289-300.


Blanchard RJ, Ohl F, van Kampen M, Blanchard DC, Fuchs E (2001): Attack and defense in conspecific fighting in tree shrews (Tupaia belangeri). Aggr. Behav. 27: 139-148.


Isovich E, Engelmann M, Landgraf R, Fuchs E (2001): Single social defeat reduces striatal dopamine transporter binding in rats: effects of housing conditions. Eur J Neurosci 13: 1254-56.


Fuchs E, Flügge G (2001): Psychosoziale Belastung als Ursache molekularer und struktureller Veränderungen im Gehirn. Wie tierexperimentelle Untersuchungen zum Verständnis der Pathomechanismen depressiver Erkrankungen beitragen können. Z Psychosom Med 47: 80-97.



Fuchs E, Gould E (2000): In vivo neurogenesis in the adult brain: regulation and functional implications. Eur J Neurosci 12: 2211-14.


Flügge G (2000): Regulation of monoamine receptors in the brain: dynamic changes during stress. Int Rev Cytology 195: 145-213.


Keuker JIH, Luiten PGM, Fuchs E (2000): Capillary changes in hippocampal CA1 and CA3 areas of the aging rhesus monkey. Acta Neuropathol (Berl)100: 665-72.


Meyer H, Palchaudhuri M, Scheinin M, Flügge G (2000): Regulation of alpha2A-adrenoceptor expression by chronic stress in neurons of the brain stem. Brain Res 880: 147-158.


Isovich E, Mijnster MJ, Flügge G, Fuchs E (2000): Chronic psychosocial stress reduces the density of dopamine transporters. Eur J Neurosci 12: 1071-78.


Ohl F, Michaelis T, Vollmann-Honsdorf GK, Kirschbaum C, Fuchs E (2000): Effect of  chronic psychosocial stress and long-term cortisol treatment on hippocampus-mediated memory and hippocampal volume: a pilot-study in tree shrews. Psychoneuroendocrinol 25: 35-363.


van Kampen M, Schmitt U, Hiemke C, Fuchs E (2000): Diazepam has no beneficial effects on stress-induced behavioral and endocrine changes in male tree shrews. Biochem Pharmacol Behav 65: 539-546.


Fuchs E, Kempermann G, Winkler J, Kuhn HG (2000): Neurogenese – ein neues Konzept für den Ersatz von Nervenzellen im Gehirn. In: Sames K (ed): Medizinische Regeneration und Tissue Engineering. Neue Techniken der Erhaltung und Erneuerung von Gewebefunktionen. Ecomed Verlagsgesellschaft, Landsberg, V9 /1- V9/7.



Kramer M, Hiemke C, Fuchs E (1999): Chronic psychosocial stress and antidepressant treatment in tree shrews: time-dependent behavioral and endocrine effects. Neurosci Biobehav Rev 23: 937-947.


Ohl F, Michaelis T, Fujimori H, Frahm J, Rensing S, Fuchs E (1999): Volumetric MRI measurements of the tree shrew hippocampus. J Neurosci Meth 88: 189-193.


Mijnster MJ, Isovich E, Flügge G, Fuchs E (1999): Localization of dopamine D1- like and D2- like binding sites in the tree shrew brain using [3H]-SCH23390 and [125I]-epidepride. Brain Res 841: 101-113.


Fuchs E (1999): Tree shrews. In: Poole T (ed) UFAW handbook on the care and management of laboratory animals. 7th Ed., Vol. I Terrestrial Vertebrates, Blackwell, Oxford: 235-245. 


Gould E, Reeves AJ, Fallah M, Tanapat P, Gross CG, Fuchs E (1999): Hippocampal neurogenesis in adult Old World primates. Proc Natl Acad Sci USA 96: 5263-67.


Palchaudhuri MR, Hauger RL, Wille S, Fuchs E, Dautzenberg FM (1999): Isolation and pharmacological characterization of two functional splice variants of corticotropin-releasing factor type 2 receptor from Tupaia belangeri. J Neuroendocrinol 11: 419-428.


Kole MHP, Fuchs E, Ziemann U, Paulus W, Ebert U (1999): Changes in seizure susceptibility and NMDA and 5-HT1A binding sites by a single rapid transcranial magnetic stimulation procedure in rats.

Brain Res. 826: 309.


Ohl F, Fuchs E (1999): Differential effects of chronic stress on memory processes in the tree shrew. Cog Brain Res 7: 379-387.


Flügge G, Pfender D, Rudolph S, Jarry H, Fuchs E (1999): 5HT1A-receptor binding in the brain of cyclic and ovarectomized female rats. J Neuroendocrinol 11: 243-249.



Fuchs E, Flügge G (1998): Stress, glucocorticoids and structural plasticity of the hippocampus. Neurosci Biobehav Rev 23: 295-300.


Ohl F, Fuchs E (1998): Memory performance in tree shrews: Effects of stressful experiences. Neurosci Biobehav Rev 23: 319-323.


Palchaudhuri MR, Wille S, Mevenkamp G, Spiess J, Fuchs E, Dautzenberg F (1998): Corticotropin-releasing factor type 1 from Tupaia belangeri : cloning, functional expression and tissue distribution.

Eur J Biochem 258: 78-84.


van Kampen M, Fuchs E (1998): Age-related levels of urinary free cortisol in the tree shrew.

Neurobiol Aging 19: 363-366.


Flügge G, Kramer M, Rensing S, Fuchs E (1998): 5HT1A-receptors and behaviour under chronic stress: selective counteraction by testosterone. Eur J Neurosci 10: 2685-93.


Ohl F, Oitzl MS, Fuchs E (1998): Assessing cognitive functions in tree shrews: Visuo-spatial and spatial learning in the home cage. J Neurosci Meth 81: 35-40.


Meyer U, Kruhøffer M, Flügge G, Fuchs E (1998): Cloning of glucocorticoid receptor and mineralocorticoid receptor cDNA and gene expression in the central nervous system of the tree shrew (Tupaia belangeri). Mol Brain Res 55: 243-253.


Gould E, Tanapat P, McEwen BS, Flügge G, Fuchs E (1998): Proliferation of granule cell precursors in the dentate gyrus of adult monkeys is diminished by stress. Proc Natl Acad Sci USA 95: 3168-3171.


Jeffery G, Harman A, Flügge G (1998): First evidence of diversity in eutherian chiasmatic architecture: tree shrews, like marsupials, have spatially segregated crossed and uncrossed chiasmatic pathways.

J Comp Neurol 390: 183-93.



Vollmann-Honsdorf GK, Flügge G, Fuchs E (1997): Chronic psychosocial stress does not affect the number of pyramidal neurons in tree shrew hippocampus. Neurosci Lett 233: 121-124.


Flügge G, Ahrens O, Fuchs E (1997): Beta-adrenoceptors in the tree-shrew brain: I. Distribution and characterization of 125I-iodocyanopindolol binding sites. Cell Mol Neurobiol 17: 401-415.


Flügge G, Ahrens O, Fuchs E (1997): Beta-adrenoceptors in the tree-shrew brain: II. Time dependent effects of chronic psychosocial stress on 125I-idocyanopindolol binding sites. Cell Mol Neurobiol 17: 417-432.


Gould E, McEwen BS, Tanapat P, Galea LAM, Fuchs E 81997): Neurogenesis in the dentate gyrus of the adult tree shrew is regulated by psychosocial stress and NMDA receptor activation. J Neurosci 17: 2492-2498.


Flügge G, Ahrens O, Fuchs E (1997): Monoamine receptors in the prefrontal cortex of Tupaia belangeri during psychosocial stress. Cell Tissue Res 288: 1-10.