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MRI und MRS of the Brain

Brain development and aging

Comparative studies in rodents, non-human primates and humans

Leibniz Research Alliances
Healthy aging

Influence of anesthetics on the brain

MRS_Lac

Studies on the changes in brain metabolism
(Boretius et al., 2011, Fünfschilling et al., 2012)

Influence of Anesthetics on Neuronal Activity and Hemodynamic Coupling - Implications for Preclinical Research (Publication and Data)

Burst Suppression and Anesthetics
(PhD project Nikoloz Sirmpilatze)

Inflammatory and degenerative diseases of the brain

T2_T1

myo-inositol as a marker for (micro)-glial cell activation
(Poggi et al., 2016; Janova et al., 2018)

Interaction of neuron and glial cells
(Supplie et al., 2017)

Permeability of the blood-brain barrier
(Huhndorf et al., 2016; Pan et al., 2017)

Methods

Spatially high-resolution in vivo MRT

Multi-contrast MRI

BOLD fMRT

fmri

(Functional) localized magnetic resonance spectroscopy (MRS)

MRS

Cerebral perfusion and blood-brain barrier

CBV