We study genes that control the immune response. We are particularly interested in the biology of natural killer (NK) cells.
Selected Projects
- Genetic diversity and function of NK cell receptors and MHC class I of non-human primates
- Function of human NK cell receptors
- Transcriptomic analyses of NK cells and other innate lymphoid cells (ILC)
Methods
- Next-generation sequencing (RNA-seq, Amplicon seq, ATAC-seq)
- Single cell genomics (RNA-seq)
- Bioinformatic analyses of NGS data
- Flow cytometry
- Establishment and usage of monoclonal antibodies
- Biochemical methods (affinity chromatography, binding assays)
- Immunological assays